• Kiefer Sutherland as Jack Bauer
• Mary Lynn Rajskub as Chloe O’Brian
• DB Woodside as President Wayne Palmer
• James Morrison as Bill Buchanan
• Peter MacNicol as Tom Lennox
• Jayne Atkinson as Karen Hayes
• Carlo Rota as Morris O’Brian
• Eric Balfour as Milo Pressman
• Marisol Nichols as Nadia Yassir
• Regina King as Sandra Palmer

Special Guest Stars

• Powers Boothe as Vice President Noah Daniels
• James Cromwell as Philip Bauer
• Kim Raver as Audrey Raines
• Gregory Itzin as Charles Logan
• William Devane as James Heller
• Jean Smart as Martha Logan

• Adoni Maropis as Abu Fayed
• Rena Sofer as Marilyn Bauer
• Ricky Schroder as Mike Doyle
• Evan Ellingson as Josh Bauer
• Kari Matchett as Lisa Miller
• Tzi Ma as Cheng Zhi
• Chad Lowe as Reed Pollock
• Rade Šerbedžija as Dmitri Gredenko
• Alexander Siddig as Hamri Al-Assad
• Nick Jameson as Russian President Yuri Suvarov
• Harry Lennix as Walid Al-Rezani
• Ryan Cutrona as Admiral John Smith
• Roger Cross as Curtis Manning
• Kal Penn as Ahmed Amar
• David Hunt as Darren McCarthy
• Paul McCrane as Graem Bauer
• Bob Gunton as Secretary of Defense Ethan Kanin
• Glenn Morshower as Aaron Pierce
• Kathleen Gati as Russian First Lady Anya Suvarov